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Product Details 基本信息 ISBN-13 书号 9783030294410 Author 作者 Br?uning Format 版本 平装-胶订 Pages Number 页数 86页 Publisher 出版社 Springer Berlin Heidelberg Publication Date 出版日期 2020-10-09 Language 语种 英语 Book Contents 内容简介 This book discusses the decoding of the lytic mechanism of an -helical pore-forming toxin, YaxAB, composed of two different subunits. Pore-forming toxins (PFTs) are among the most common bacterial toxins. They are produced by a variety of pathogens, which infect a wide range of organisms including plants, insects and humans. Yet the maturation of these particles and the structural changes required for pore formation are still poorly understood for many PFT families.Using a diverse panel of biochemical and structural techniques, including X-ray crystallography and cryo-electron microscopy, Dr. Br?uning and colleagues have succeeded in identifying the mechanistic contr
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