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Ibragimov, Nail H. /1995-10-23 /CRC Press

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Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early dissemination of its findings. Group sequential methods provide a means to balance the ethical and financial advantages of stopping a study early against the risk of an incorrect conclusion. Group Sequential Methods with Applications to Clinical Trials describes group sequential stopping rules designed to reduce average study length and control Type I and II error probabilities. The authors present one-sided and two-sided tests, introduce several families of group sequential tests, and explain how to choose the most appropriate test and interim analysis schedule. Their topics include placebo-controlled randomized trials, bio-equivalence testing, crossover and longitudinal studies, and linear and generalized

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Christopher Jennison| Bruce W. Turnbull /1999-09-15 /taylor

海外直订Linear Algebra and Group Theory for Physicists a... 物理学家

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D.L. Johnson /1988-08-08 /Cambridge UniversityPress

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Ibragimov,Nail H ; Anderson,Robert L ; B /1995-10-24 /CRC Press

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Product Details 基本信息 ISBN-13 书号 9783319819037 Author 作者 * Pelleg Format 版本 平装-胶订 Pages Number 页数 362页 Publisher 出版社 Springer Berlin Heidelberg Publication Date 出版日期 2018-04-28 Language 语种 英语 Book Contents 内容简介 This book explores diffusion in L12 and B2 structures of Ni3Al, Ni3Ge, Ni3Ga and NiAl, NiGe and NiGa and discusses Fe- and Co-based alloys in detail. These alloys of the VIIIA group elements are the basis of intermetallic compounds known as ’super alloys,’ which are important in many technological high-temperature structural applications to improve mechanical strength properties such as creep. Knowledge of diffusion behavior of intermetallic solids is critical, in particular in high temperature applications of material. Development of high temperature alloys depends on the understanding of diffusion in the aforementioned compounds. Therefore, this comprehensive

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Karoll, Carolyn /2024-04-24 /Routledge

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K?nig, Karl /1994-07-31 /Jason Aronson

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2008-02-29 /World Scientific Publishing Company

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