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Product Details 基本信息 ISBN-13 书号 9781489992413 Author 作者 * Format 版本 平装-胶订 Pages Number 页数 372页 Publisher 出版社 Springer New York Publication Date 出版日期 2014-10-15 Product Dimensions 商品尺寸 9.2 x 6.1 x 0.7 cm Shipping Weight 商品重量 587g Language 语种 英语 Book Contents 内容简介 Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation. Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due to the fact that protein components of the respiratory chain are encoded by both mitochondrial and nuclear genomes and are essential in all cells.? In addition, the biogenesis, structure and function of mitochondria, including DNA replication, tran*ion, and translation, all require nuclear encoded genes.? Since mitochondria are present in every cell, every
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