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Product Details 基本信息 ISBN-13 书号 9781071616642 Author 作者 Angela M. Cacace Format 版本 精装 Pages Number 页数 364页 Publisher 出版社 Humana Press Publication Date 出版日期 2021-07-26 Language 语种 其它(含多语) Book Contents 内容简介 This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successfulMethods in Molecular Biologyseries, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.Author
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