【预售 按需印刷】Testosterone and its dimers alter DNA and tRNA morp
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【预售 按需印刷】DNA and RNA Structural Changes by Antioxidant Tea C
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【预售 按需印刷】The Effects of Vitamins on DNA and RNA Structures a
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海外直订DNA and RNA Structural Changes by Antioxidant Tea Catech
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【预订】Control of Flexible-Link Manipulators Using Neural 美国库房发货,通常付款后3-5周到货!
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预订 高被引Neural Network-Based State Estimation of Nonlinear Sys 【全球购】进口原版图书,约5-8周到达国内后发出
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【预售 按需印刷】Gene Delivery by Protein-Polymer Nanoconj
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【预售 按需印刷】Delivery of Vitamins A, B and C by Serum 北京发货,付款后10天内发货
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按需印刷Effect of Antioxidant Polyphenols on DNA and RNA Structu 预订,预计下单后2-3周左右发货!
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按需印刷The anticancer drug doxorubicin binds DNA and RNA at dif 预订,预计下单后2-3周左右发货!
¥471.00
按需印刷Delivery of Vitamins A, B and C by Serum Proteins 预订,预计下单后2-3周左右发货!
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海外直订Delivery of Vitamins A, B and C by Serum Proteins 血清蛋白输送
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【预订】Effect of Antioxidant Polyphenols on DNA and RNA Structu 国外库房发货,通常付款后3-5周到货!
Product Details 基本信息 ISBN-13 书号 9783330870062 Author 作者 Heidar-Ali Tajmir-Riahi Format 版本 平装-胶订 Pages Number 页数 76页 Publisher 出版社 EUE Editions Universitaires Européennes Publication Date 出版日期 2017-05-03 Language 语种 其它(含多语) Book Contents 内容简介 The effects of antioxidant polyphenols on DNA and tRNA structures were evaluated in aqueous solution at physiological conditions. Structural models show that intercalation with DNA is more stable for resveratrol and genistein than groove bindings, while curcumin interaction is via DNA grooves. Polyphenols prefer tRNA groove binding with DNA forming stronger adducts than tRNA. Theoretical modeling showed more stable conjugates formed with resveratrol and genistein than curcumin. At high polyphenol concentration major DNA and RNA aggregation occurred, with no alteration of biopolymer conformation.
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【预售 按需印刷】Effect of Antioxidant Polyphenols on DNA 北京发货,付款后10天内发货
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海外直订Gene Delivery by Protein-Polymer Nanoconjugates 蛋白质-聚合物纳
¥317.00
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【预订】Breast anticancer drug tamoxifen and its metabolites bin 国外库房发货,通常付款后3-5周到货!
Product Details 基本信息 ISBN-13 书号 9783330873933 Author 作者 Heidar-Ali Tajmir-Riahi Format 版本 平装-胶订 Pages Number 页数 84页 Publisher 出版社 EUE Editions Universitaires Européennes Publication Date 出版日期 2017-05-31 Language 语种 其它(含多语) Book Contents 内容简介 Tamoxifen is a breast anticancer drug that has been in worldwide use for the treatment of estrogen receptor (ER)-positive breast cancer for over 30 years. We compare the binding sites of the tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen with DNA and tRNA. Structural models showed that tamoxifen and its metabolites bind DNA and tRNA at multiple sites via hydrophobic, hydrophilic and H-bonding contacts with tRNA forming more stable drug conjugates than DNA. Drug conjugation did not alter DNA and tRNA conformations, while major biopolymer aggregation occurred at high drug contents. The drug loading efficacy is
¥353.00
按需印刷Breast anticancer drug tamoxifen and its metabolites bin 预订,预计下单后2-3周左右发货!
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【预订】The anticancer drug doxorubicin binds DNA and RNA at dif 国外库房发货,通常付款后3-5周到货!
Product Details 基本信息 ISBN-13 书号 9783330877061 Author 作者 Heidar-Ali Tajmir-Riahi Format 版本 平装-胶订 Pages Number 页数 96页 Publisher 出版社 EUE Editions Universitaires Européennes Publication Date 出版日期 2017-06-21 Language 语种 其它(含多语) Book Contents 内容简介 In the past 50 years, doxorubicin (DOX) known as adriamycin remains one of the most effective chemotherapeutic anticancer drugs for the treatment of different types of cancers. We compare the binding sites of doxorubicin with DNA and tRNA. DOX binding is via intercalation into DNA duplex, while it binds to tRNA through major and minor grooves. DOX-DNA intercalation is close to A-7, C-5, *C-19 (H-bonding with DOX NH2 group), G-6, T-8 and T-18 with the free binding energy of -4.99 kcal/mol. DOX-tRNA bindings are near A-29, A-31, A-38, C-25, C-27, C-28, *G-30 (H-bonding) and U-41 with the free binding energy of -4.44 kcal/mol.
¥486.00
海外直订The Effects of Vitamins on DNA and RNA Structures and Dy
¥470.00
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海外直订Neural Network-Based State Estimation of Nonlinear Syste
¥1193
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按需印刷Testosterone and its dimers alter DNA and tRNA morpholog 预订,预计下单后2-3周左右发货!
¥327.00
【预售 按需印刷】The anticancer drug doxorubicin binds DNA 北京发货,付款后10天内发货
¥471.00
【预售 按需印刷】Breast anticancer drug tamoxifen and its
¥290.70